NeuroFactor® by FutureCeuticals
NeuroFactor® by FutureCeuticals
NeuroFactor® is a patented, all-natural extract derived from whole Coffea arabica coffee fruit. It is clinically shown to significantly increase brain-derived neurotrophic factor (BDNF), essential for learning, memory, and cognitive function. NeuroFactor® is vegan, non-GMO, kosher, and free from PHOs. Available in both conventional and organic forms, it offers versatility for cognitive health applications, providing a natural solution to support brain performance and mental clarity.
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General
Item #:
Company:
Technology:
NA
Name:
NeuroFactor®
Ingredient/s:
Green Coffee, Green Coffee Bean
Categories:
Cognitive Health, Nootropic
Dosage (min):
100mg
Dosage (max):
MOQ:
Price kg:
Botanicals:
Coffea arabica (Fruit)
Active/s:
Green Coffee, Green Coffee Bean
Assay:
Country of Origin:
Suppliers:
FutureCeuticals, Inc.
Contact Information
Email:
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Ingredient Highlights
NeuroFactor® features clinically supported actives shown to help:
- Promote BDNF production for brain health.*
- Support cognitive clarity and learning capacity.*
- Enhance mental performance and focus.*
- Improve memory and neuroplasticity measures.*
- Support brain cell communication and renewal.*
- Promote long-term cognitive resilience.*
- Support overall brain wellness and function.*
Cheat Sheet Card
100% Natural
Vegan
Gluten Free
Non-GMO
GRAS
Water Soluble
Wild-Harvested
Allergen Free
Key Certifications
Halal Certified
Kosher Certified
Vegan Certified
USDA Organic
NON-GMO Project Verified
Gluten-Free Certified
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Ingredient Highlights
NeuroFactor® features clinically supported actives shown to help:
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Science & Research - Coming Soon
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Q &A
What makes NeuroFactor® different from other nootropic ingredients?
NeuroFactor® differs from many conventional nootropic ingredients through its clinically studied relationship with brain-derived neurotrophic factor (BDNF), a protein involved in neuronal health, learning, and memory. Derived from whole Coffea arabica coffee fruit, NeuroFactor® provides naturally occurring polyphenols rather than relying on high doses of caffeine for stimulation. Human clinical research has investigated its effects on BDNF levels, working memory, attention, and cognitive performance, making it a differentiated option for supplement brands developing stimulant-free cognitive health formulations.
Clinical Reference:
Reyes-Izquierdo et al. (2013). Modulatory effect of coffee fruit extract on plasma levels of brain-derived neurotrophic factor in healthy subjects.
What does clinical research reveal about NeuroFactor® and BDNF?
Clinical research suggests that NeuroFactor® may support circulating levels of brain-derived neurotrophic factor (BDNF), a protein associated with neuronal function and synaptic plasticity. In a human pilot investigation, a single 100 mg dose of whole coffee fruit concentrate increased plasma BDNF by approximately 143% from baseline in a small group of participants. These findings generated scientific interest in coffee fruit polyphenols as a potential approach to cognitive health. However, circulating BDNF increases do not necessarily establish equivalent changes in brain BDNF or improvements in cognitive performance.
Clinical Reference:
Reyes-Izquierdo et al. (2013). Modulatory effect of coffee fruit extract on plasma levels of brain-derived neurotrophic factor in healthy subjects.
https://pubmed.ncbi.nlm.nih.gov/23312069/
How quickly does NeuroFactor® work according to clinical studies?
Human research has identified measurable effects of whole coffee fruit extract within hours of supplementation, although results depend on the outcome being evaluated. An early study reported changes in circulating BDNF following a single 100 mg dose, while a 2024 randomized, double-blind, placebo-controlled trial found improvements in selected working-memory and response-inhibition measures one hour after a 200 mg dose. The same 28-day trial also reported benefits on certain working-memory accuracy measures during continued supplementation. These findings suggest potential for both acute and longer-term cognitive support, rather than establishing a guaranteed onset of noticeable benefits.
Clinical References:
Reyes-Izquierdo et al. (2013). Modulatory effect of coffee fruit extract on plasma levels of brain-derived neurotrophic factor in healthy subjects.
https://pubmed.ncbi.nlm.nih.gov/23312069/
Robinson et al. (2024). Whole Coffee Cherry Extract Improves Working Memory and Response Inhibition: Acute and Longitudinal Results from a Remote, Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
https://pubmed.ncbi.nlm.nih.gov/39064791/
Can NeuroFactor® be formulated with other cognitive health ingredients?
Yes. NeuroFactor® can be incorporated into multi-ingredient cognitive health formulations alongside complementary nootropics. Its low-caffeine, polyphenol-rich profile offers formulators an alternative to stimulant-driven approaches. Published human clinical research has evaluated whole coffee fruit extract in combination with Bacopa monnieri and American ginseng, including studies investigating working memory, attention, and cognitive performance. This research demonstrates the ingredient’s use in multi-ingredient formulations and creates opportunities for supplement brands developing differentiated cognitive health products.
Clinical References:
Best et al. (2020). Acute effects of combined Bacopa, American ginseng and whole coffee fruit on working memory and cerebral haemodynamic response of the prefrontal cortex: a double-blind, placebo-controlled study.
https://pubmed.ncbi.nlm.nih.gov/31736428/
Best et al. (2024). Neurocognitive effects of a combined polyphenolic-rich herbal extract in healthy middle-aged adults—a randomised, double-blind, placebo-controlled study.
https://pubmed.ncbi.nlm.nih.gov/38512715/
Does NeuroFactor® contain caffeine?
NeuroFactor® is a low-caffeine whole coffee fruit extract designed to support cognitive health without relying on caffeine as its primary mechanism of action. Although derived from Coffea arabica, the clinically studied extract contains less than 2% caffeine, equivalent to less than 4 mg in a 200 mg serving. Its cognitive health positioning centers on naturally occurring coffee fruit polyphenols and their relationship to brain-derived neurotrophic factor (BDNF), rather than traditional caffeine-driven stimulation. This makes NeuroFactor® an attractive option for formulators developing cognitive health, memory, and focus supplements with minimal added caffeine.
Clinical Reference:
Robinson et al. (2024). Whole Coffee Cherry Extract Improves Working Memory and Response Inhibition: Acute and Longitudinal Results from a Remote, Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
https://pubmed.ncbi.nlm.nih.gov/39064791/
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