
HomeSpecialty IngredientBermax™ by Botanic Healthcare
Bermax™ by Botanic Healthcare
Bermax™ by Botanic Healthcare
Bermax™ by Botanic Healthcare is a liposomal berberine extract designed to enhance absorption and bioavailability compared to conventional forms. Derived from Berberis aristata, it is standardized to 35% berberine and formulated using liposomal delivery technology to improve cellular uptake and stability. This advanced ingredient supports formulation needs in metabolic health and gut health categories. Its water-dispersible characteristics provide improved solubility and functional versatility for nutraceutical, food, and beverage applications. Certifications such as Non-GMO, Kosher, and Halal are available.
General
Item #:
Company:
Technology:
Liposomal delivery technology
Name:
Bermax™
Ingredient/s:
Berberine
Categories:
Glucose Metabolism, Gut Health, Metabolic Health, Detox, Support regularity
Dosage (min):
Dosage (max):
MOQ:
Price kg:
Botanicals:
Berberis aristata
Active/s:
Berberine
Assay:
Standardized to 35% berberine
Country of Origin:
Suppliers:
Botanic Healthcare
Contact Information
Email: info@nxtingredients.com
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Ingredient Highlights
Bermax™ is clinically researched and shown to help:
- Support healthy blood sugar levels.*
- Promote cardiovascular health.*
- Help assist with weight management.*
- Enhance nutrient absorption.*
- Offer antioxidant protection.*
- Help improve gut health.*
Cheat Sheet Card
100% Natural
Vegan
Gluten Free
Non-GMO
GRAS
Water Soluble
Wild-Harvested
Allergen Free
Key Certifications
Halal Certified
Kosher Certified
Vegan Certified
USDA Organic
NON-GMO Project Verified
Gluten-Free Certified
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Ingredient Highlights
Bermax™ is clinically researched and shown to help:
Q &A
What makes Bermax™ different from conventional berberine supplements?
Bermax™ by Botanic Healthcare is a liposomal berberine ingredient offered at a 35% specification. Its liposomal format differentiates it from conventional, non-liposomal berberine powders and provides manufacturers with an alternative delivery format to evaluate for supplement development. Product specifications and supporting technical documentation should be reviewed to confirm its phospholipid source and any demonstrated bioavailability advantages.
Technical Reference:
Botanic Healthcare. Liposomal Ingredient Portfolio — Bermax™ (Liposomal Berberine 35%).
https://www.botanichealthcare.net/liposomes/
How does the liposomal delivery technology in Bermax™ support berberine absorption?
Bermax™ uses a phospholipid-based delivery system designed to help overcome berberine’s naturally poor oral absorption. Liposomal delivery systems incorporate phospholipids that can help protect certain bioactive compounds and influence their interaction with the gastrointestinal environment. Published studies of liposomal and other advanced berberine formulations have demonstrated improvements in solubility, intestinal permeability, and systemic exposure compared with unformulated berberine. These findings provide a scientific rationale for Bermax™’s liposomal approach, although the magnitude of any absorption advantage must be established through research on the specific Bermax™ formulation.
Research References:
Optimization of Hyaluronate-Based Liposomes to Augment the Oral Delivery and the Bioavailability of Berberine. (2021).
https://pmc.ncbi.nlm.nih.gov/articles/PMC8510464/
Purpura M, et al. (2026). Liposomal Delivery as a Strategy to Improve Berberine Bioavailability: A Double-Blind, Crossover, Randomized Pilot Study in Healthy Males.
https://doi.org/10.2147/NDS.S582434
What metabolic health benefits are associated with berberine in Bermax™?
Bermax™ provides berberine, a naturally occurring plant alkaloid extensively investigated for its relationship with glucose metabolism, insulin signaling, and lipid regulation. Human clinical studies involving berberine have reported favorable effects on selected metabolic markers, including fasting blood glucose and cholesterol levels. Research has also examined berberine’s influence on pathways involved in cellular energy regulation, including AMP-activated protein kinase (AMPK). These findings support interest in Bermax™ as an ingredient for metabolic wellness formulations, while recognizing that clinical results obtained with other berberine preparations do not automatically establish equivalent outcomes for Bermax™.
Clinical References:
Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease. (2015).
https://pmc.ncbi.nlm.nih.gov/articles/PMC4529214/
Berberine Phospholipid Exerts a Positive Effect on the Glycemic Profile of Overweight Subjects with Impaired Fasting Blood Glucose: A Randomized Double-Blind Placebo-Controlled Clinical Trial. (2023).
https://pubmed.ncbi.nlm.nih.gov/37522683/
Has liposomal berberine been clinically studied for improved bioavailability?
Yes. Published human research has evaluated whether liposomal berberine can improve absorption compared with conventional berberine powder. In a 2026 randomized, double-blind, crossover pilot study involving six healthy men, participants received a single 400 mg dose of berberine in each formulation. The liposomal formulation produced significantly higher peak plasma concentrations (Cmax) and systemic exposure over 24 hours (AUC₀–₂₄) than unformulated berberine. Median Cmax values were approximately 2.08 times as high, while median AUC₀–₂₄ values were approximately 1.54 times as high. These exploratory findings support further investigation of that specific liposomal formulation; larger studies are needed to confirm their generalizability. The study evaluated Specnova’s LipoVantage® formulation, not Bermax™, so its absorption findings should not be presented as Bermax™-specific clinical results.
Clinical Reference:
Purpura M, et al. (2026). Liposomal Delivery as a Strategy to Improve Berberine Bioavailability: A Double-Blind, Crossover, Randomized Pilot Study in Healthy Males. Nutrition and Dietary Supplements.
https://doi.org/10.2147/NDS.S582434
What should formulators know about the 35% berberine specification in Bermax™?
Bermax™ by Botanic Healthcare is a liposomal berberine ingredient standardized to contain not less than 35% berberine, as determined by HPLC. Its formulation combines berberine hydrochloride with sunflower lecithin and maltodextrin in a specialized delivery system. At the stated minimum 35% specification, a 500 mg inclusion level corresponds to 175 mg of berberine, subject to the supplier’s assay reporting basis. This distinction is important when comparing Bermax™ with conventional high-purity berberine hydrochloride powders. For supplement manufacturers, the defined active-content specification provides a practical basis for evaluating formulation inclusion levels, serving sizes, and metabolic health product development.
Technical References:
Botanic Healthcare. Bermax™ (Liposomal Berberine 35%) — Composition Statement. June 9, 2025.
https://ss3-production-public.s3.amazonaws.com/seller-document/250/E895EAA89B90F480FD69B8FDA324D8D4.pdf
Botanic Healthcare. Bermax™ — Product Specification and Technical Data Sheet.
https://ss3-production-public.s3.amazonaws.com/seller-document/250/41F45F773C4F4CF65A7AA4AB47B5FCD4.pdf
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